Cancer: Photodynamic Therapy (PDT)

Light activated anticancer drug targeted to DNA using cisplatin like sub-units: Coupling light absorbers to reactive metal centers. ‘One of the most effective chemotherapy drugs against cancer is cisplatin because it attaches to cancer DNA and disrupts repair. However, it also kills healthy tissue. Many scientists are creating alternative drugs or cisplatin analogs in attempts to find treatments without side effects. One approach to analog development is light activated drugs, or photodynamic therapy (PDT). Now a Virginia Tech chemistry-biology research team that has been working on both non-cisplatin drugs and cisplatin analogs has combined their findings to create a molecular complex (supramolecule) that exploits cisplatins tumor targeting to deliver a light activated drug.’

National Cancer InstitutePhotodynamic Therapy for Cancer: Questions and Answers

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