CAS Science Spotlight, already mentioned here, has been updated. The 4Q-2004 data as well as 2004 annual data have been added, except the most cited articles list. The author with the highest number of requested articles from CAS electronic services worldwide during 2004 was Stephen L. Buchwald of Massachusetts Institute of Technology. The most requested journal article was Toward Catalytic Rigid-rod ß-barrels: a Hexamer with Multiple Histidines, by Gopal Das, Naomi Sakai and Stefan Matile, published on Chirality. The complete list of the most requested documents, articles and patents, can be found here.